Xenium Spatial Platform

Unparalleled single cell spatial discovery

Characterize 100s to 1,000s of RNAs in cells and tissues with subcellular in situ resolution.

The ultimate single cell spatial biology experience

The Xenium platform delivers high-plex in situ at subcellular resolution with nanometer precision and offers a complete solution, including comprehensive panel offerings, to achieve fast and robust single cell spatial insights.
10x Genomics Xenium platform

Gene and protein panels

Customizable ready-to-use panels or fully custom gene panels with add-on protein subpanels

Xenium Analyzer instrument

Industry-leading speed and throughput for single cell spatial imaging

Data analysis

Powerful on-board analysis and Xenium Explorer visualization software

Xenium Protein
Now shipping!

Same-cell spatial multiomics with Xenium Protein

  • A first-of-its-kind fully optimized & automated solution for integrated high-plex spatial RNA and protein expression

  • Validated, ready-to-use immuno-oncology-focused protein and gene panels eliminate the need for optimization

  • Single-instrument workflow enables integrated analysis in Xenium Explorer, no data registration required

Built for rapid data exploration

Immediate data access

Access your data as soon as the Xenium run is complete.

Easy-to-use interface

Intuitively visualize morphology, protein markers, segmentation, cell typing, and transcript density—no bioinformatics experience required.

Explore at any scale

Seamlessly explore your data at any scale, from whole tissue sections to single transcripts.

Diverse panel menu to fit any research need

<500-gene panels

Focused tissue and pathway characterization

  • Full custom panel option

  • Multiomic analysis with Xenium Protein subpanels

5,000-gene panels

Broad discovery in human and mouse

  • Customizable with up to 100 additional genes

  • Explore across tissues, disease areas, and drug targets

A state-of-the-art single cell spatial imaging instrument

  • Seamlessly integrates transcript detection workflow, high-resolution imaging, decoding, and onboard data analysis for fresh frozen or FFPE tissues

  • Simple run setup and cleanup operations, an intuitive touchscreen, and ergonomic design make instrument operation a breeze

  • Go from tissue section to data for up to 5,000 genes in ≤6 days or get even faster analysis times with smaller gene panels

Xenium Catalyst Program

Discover the power of Xenium technology with our in-house pilot run service

Our Catalyst program lets you test drive the Xenium platform, evaluate its capabilities, and explore your spatial transcriptomics data alongside a team of scientific experts.

4 weeks

End-to-end service completed in as few as

10+ panels

Complete access to fully custom or

Learn how it works

Resources

See Xenium Protein data in action

Get a hands-on look at what same-section protein and high-plex spatial RNA can show you in this interactive Xenium web demo.

Get to know the Xenium platform

Explore the unique platform features, from padlock chemistry to panels, that power the ultimate single cell spatial biology experience.

Grant writing assistance

Get the information you need to write grants featuring Xenium experiments (including technology overview, benchmarking data, and more).

See what Xenium users are saying

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Unlock the full spectrum of biology

Build on your Xenium Spatial insights with comprehensive, whole transcriptome single cell and spatial analysis.See how researchers used Chromium, Visium, and Xenium assays to study human lung development
Platform
Chromium Single Cell platform

Chromium Single Cell platform

Learn more
Xenium Spatial platform

Xenium Spatial platform

See Xenium panels
Visium Spatial platform

Visium Spatial platform

Learn more
When to use
Comprehensive single cell dataIdeal for deep characterization of cell populations and states.
High-resolution discoveryUnderstand complex tissues, neighborhoods, and cell to cell interactions. Integration with other spatial-omics, histology, and morphology.
Why use
Unbiased single cell discovery High per-gene sensitivity
Single cell spatial discovery High per-gene sensitivity
Expanded spatial discovery
Applications
Whole transcriptome gene expression Protein TCR, BCR CRISPR ATAC
Targeted gene expression (up to 5,000 genes) Multiomic gene and protein expression (up to 480 genes and 27 proteins)
Whole transcriptome gene expression
Resolution
Single cell
Subcellular
Single cell–scale
Data readout
NGS-based
Imaging-based
NGS-based
Sample compatibility
Single cell or nuclei suspensions from fresh, frozen, or FFPE samples
Fresh frozen FFPE
FFPE Fresh frozen Fixed frozen

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