Xenium Panels

Ready-to-use meets unmatched customization

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Design a custom panel

Complete flexibility for your research

Single cell spatial discovery at any scale

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Overview
<500-gene panels icon

<500-gene panels

Focused tissue and pathway characterization

  • Full custom panel option
  • Multiomic analysis with Xenium Protein subpanels
5,000-gene panels icon

5,000-gene panels

Broad discovery in human and mouse

  • Customizable with up to 100 additional genes
  • Explore across tissues, disease areas, and drug targets
Products
Chemistry
  • RNA v1
  • Xenium Prime
Panel sizes
  • 50–480 genes
  • 5,000 genes
Panel types
  • Ready-to-use panels
  • Custom panels
  • Ready-to-use panels
Customization
  • Xenium Panel Designer
  • Add on up to 100 genes to pre-designed panels
  • Design fully custom panels up to 480 genes
  • Xenium Panel Designer
  • Add on up to 100 genes
Compatible species
  • HumanHuman
  • MouseMouse
  • Additional species with custom panelsAdditional species with custom panels
  • HumanHuman
  • MouseMouse
Compatible samples
  • FFPE tissueFFPE tissue
  • Fresh frozen tissueFresh frozen tissue
  • Tissue microarray (TMA)Tissue microarray (TMA)
  • FFPE tissueFFPE tissue
  • Fresh frozen tissueFresh frozen tissue
  • Tissue microarray (TMA)Tissue microarray (TMA)
Same-section capabilities
  • Gene expressionGene expression
  • Protein (IF)Protein (IF)
  • Morphology (H&E)Morphology (H&E)
Throughput
  • 2 Xenium slides per run (up to 472 mm² of tissue)
  • ~3 days per run (+2 days with Xenium Protein subpanel add-on)
  • 2 Xenium slides per run (up to 472 mm² of tissue)
  • <6 days per run
Xenium V1 graphic
Find a Xenium panel

The Xenium Panel Selector helps you find the right panel, letting you filter by and/or enter genes to check overlap with 10x Genomics pre-designed panels. It also highlights genes for custom add-on panels.

Go to Xenium Panel Selector
Ready-to-use protein subpanels

Unlock multiomic insights

Reveal functional outcomes of gene expression changes, cross-validate biomarkers, and enhance drug target identification.

    Streamlined RNA and protein profiling with a same section, same run workflow
    Easy to use, pre-optimized, validated protein subpanels
Xenium Protein subpanels | Add on to <500-gene human panels | FFPE tissue compatible
Xenium Protein subpanels are flexibly designed to be run collectively or modularly, enabling comprehensive cell typing and spatial characterization of the immune and tumor microenvironment.
Immune Cell Subpanel A
CD3, CD4, CD8, CD20
Immune Cell Subpanel B
HLA-DR, CD68, CD11c, CD138
Immune Cell Subpanel C
Granzyme B, CD163, CD16
Immune Checkpoint Subpanel
PD-1, PD-L1, VISTA, LAG3
Tumor Subpanel
PanCK, CD31, Beta-catenin, PTEN
Proliferation & Differentiation Subpanel
CD45RA, CD45RO, PCNA, Ki-67
Cell Segmentation Markers
E-cadherin, Vimentin, AlphaSMA, CD45
Custom RNA Panels

Ultimate versatility

Target unique gene markers, expression signatures, and cell types.

Design a custom panel
    Intuitive Custom Panel Designer software for full custom and add-on panels
    Advanced custom designs for isoforms, SNVs, TCR/BCR, xenografts, and viral/bacterial sequences

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