Best-in-class spatial data quality with complete coverage
The Visium platform delivers unbiased, whole transcriptome spatial gene expression analysis at single cell scale with unmatched spatial data quality and offers a flexible assay portfolio to study a broad range of tissues.
Visium slides and reagents
High-resolution, whole transcriptome spatial gene expression across species and tissue conditions
Visium CytAssist instrument
Enables a histology-friendly workflow and provides high spatial fidelity
Data analysis
Free, easy-to-use software for intuitive data visualization and exploration
Now compatible with fresh frozen, fixed frozen, and FFPE
Introducing a new era of spatial discovery with Visium HD Spatial Gene Expression
- Whole transcriptome analysis at single cell-scale resolution
- Continuous tissue coverage
- Best-in-class data powered by innovative probe-based chemistry and a Visium CytAssist-enabled workflow
Whole transcriptome spatial biology at the resolution you need
Our Visium v1/v2 and Visium HD product lines offer distinct slide architecture and multiple chemistries to explore the whole transcriptome spatial biology of your samples at the resolution you need.
Visium HD assays
Single cell–scale resolution
Probe-based chemistry
- Human and mouse FFPE, fresh frozen, and fixed frozen tissue
Reverse transcription-based chemistry
- Species agnostic, fresh frozen tissue
Multiomic readouts from the same section
- Gene expression
- Protein co-detection (immunofluorescence)
- Morphology (H&E)
Visium v1 and v2 assays
1-10 cell resolution
Probe-based chemistry (v2)
- Human and mouse FFPE, fresh frozen, and fixed frozen tissue
Reverse transcription–based chemistry (v1)
- Species agnostic, fresh frozen tissue
Multiomic readouts from the same section
- Gene expression
- Protein co-detection (immunofluorescence)
- Morphology (H&E)
- Human immuno-oncology protein panel (v2)
Unmatched spatial data quality with a histology-friendly workflow
- Ensure high spatial fidelity through precise transcript localization facilitated by the Visium CytAssist instrument
- Leverage a standard histological workflow to section, stain, and image tissues directly on glass slides
- Pre-screen and orient tissue sections to align the most desired region of tissue onto the Capture Area of the Visium slide
Accelerate spatial discovery with intuitive data exploration
Simple, fast analysis with Space Ranger
- Upload FASTQ files to 10x Cloud Analysis or download our free software for local analysis
- Process spatial sequencing data with imaging data in minutes, no command line required
Immediate insights with powerful data visualization
- Visualize and explore thousands of spatially variable genes in a few clicks with Loupe Browser
- Explore gene expression clusters in the tissue context to define cell types or gene signatures by region and morphology
Resources
See Visium HD data in action
Learn how to map the tumor microenvironment of colorectal cancer with the Visium HD assay and Loupe Browser in this guided data tutorial.
Grant writing assistance
Get the information you need to write grants featuring Visium experiments (including technology overview, benchmarking data, and more).
Spatial publications
Browse peer-reviewed publications to see how researchers have used Visium Spatial technology to accelerate novel discoveries.
Unlock the full spectrum of biology
Elevate your Visium Spatial insights with comprehensive single cell analysis or targeted, precision insights into the tissue context.
Platform |  Chromium Single Cell platform |  Visium Spatial platform |  Xenium Spatial platform |
|---|---|---|---|
When to use | Comprehensive single cell data Ideal for deep characterization of cell populations and states. | High-resolution spatial gene expression Understand complex tissues, neighborhoods, and cell to cell interactions. Integration with other spatial-omics, histology, and morphology. | |
Why to use | Unbiased single cell discovery High per-gene sensitivity | Unbiased spatial discovery | Targeted spatial exploration High per-gene sensitivity |
Applications | Whole transcriptome gene expression Protein TCR, BCR CRISPR ATAC | Whole transcriptome gene expression | Targeted gene expression (up to 5,000 genes) |
Resolution | Single cell | Transcripts assigned to 2-µm areas | Single cell |
Data readout | NGS-based | NGS-based | Imaging-based |
Sample compatibility | Single cell or nuclei suspensions from fresh, frozen, or FFPE samples | FFPE Fresh frozen Fixed frozen | Fresh frozen FFPE |