Xenium Analyzer

A state-of-the-art single cell spatial imaging platform

Seamlessly integrates transcript detection workflow, high-resolution imaging, decoding, and onboard data analysis.

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Xenium Analyzer instrument

Built to deliver exceptional image and data quality

Features state-of-the-art image acquisition and high-resolution optics with a nanometer-level localization precision.

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    Xenium offers industry-leading speed and throughput

    Using multimodal cell segmentation, analyze 472 mm² of tissue per run, targeting up to 480 genes in < 3 days or up to 5,000 genes in < 6 days.

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    Converts terabytes of 3D imaging data into biologically meaningful insights

    One-of-a-kind onboard analysis software performs high-powered computation on-instrument. Internal image sensor data is converted into ready-to-explore formats as soon your run finishes.

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    Delivers an unparalleled user experience

    Simple run setup and cleanup operations, an intuitive touchscreen, and ergonomic design make instrument operation a breeze.

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    Expands with upcoming innovations

    Flexible fluidic architecture allows the Xenium Analyzer to leverage new functionalities, assay enhancements, and more.

  • The ultimate single cell spatial biology experience

    Instrument

    Xenium Analyzer

    Xenium Analyzer

    Dimensions (W x D x H)

    52.5” x 27” x 31” (59” with door open)

    133.3 cm x 68.5 cm x 78.7 cm (149.8 cm with door open)

    Resolution

    Transcript XY-localization precision < 30 nm and Z-localization precision < 100 nm

    Pixel size = ~0.2 µm/pixel

    Number of slides per run

    2 slides

    Throughput (area per time)

    472 mm² of tissue per run when targeting up to 480 genes in < 3 days or up to 5,000 genes in < 6 days*

    Explore Runtime Planner

    Total tissue area analyzable per run

    ~ 472 mm²

    Sample prep

    2–3 days sample prep with 4–6 hrs of hands-on time

    Data output file formats

    Cell-feature matrices: MEX, HDF5, Zarr

    Transcripts and segmentation boundaries: CSV, Parquet, Zarr

    Tissue images: OME-TIFF

    Connectivity

    Compatible with 10x Genomics Cloud instrument management

    *When using multimodal cell segmentation.

    Explore the science behind Xenium

    See what Xenium users are saying

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    The Xenium In Situ platform consists of an automated analyzer, curated and/or custom panels, and intuitive visualization and analysis software.

    Xenium In Situ Platform

    Building on our years of innovation in single cell and spatial technologies, Xenium was designed to transform the way researchers can characterize RNA, protein, and cells in their native tissue environment.

    More about the Xenium platform

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