Loupe V(D)J Browser is a desktop application for Windows and macOS that allows the user to analyze, search, and visualize V(D)J sequences and clonotypes from 5' Chromium Single Cell Immune Profiling
Loupe is named for a jeweler's loupe, which is used to inspect gems.
Using Loupe V(D)J Browser, you can quickly:
- Determine the most common paired alpha and beta TCR chains or heavy and light BCR chains in your sample
- Filter clonotypes based on their antigen specificity or UMI count per antigen
- Examine full-length V, D, and J amino acid and nucleotide sequences to detect variants within V(D)J transcripts
- Search for motifs within CDR3 regions
- Compare clonotype frequencies between samples
To find out how to use Loupe V(D)J Browser to explore your data, start the tutorial.
For information on usage data sharing and instructions on how to disable it, please visit the Loupe Browser website. The process is the same for both applications.