This Tissue Preparation Guide provides guidance on:

• Best practices for handling tissue samples and Xenium slides before and after sectioning.
• Hematoxylin and Eosin (H&E) staining to check tissue quality.
• Sectioning practice and region of interest selection.
• Sectioning of tissue samples and placement of sections on Xenium slides.

Tissue Preparation Guide is compatible with Xenium In Situ Gene Expression and Xenium Prime In Situ Gene Expression.